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Metabolic and Redox regulation of cardiovascular stem cell biology and pathology

Current advances in artificial biology-enabled and pure whole-cell optical biosensing of heavy metals

 

A lot of scientific works have been printed on whole-cell heavy steel biosensing primarily based on optical transduction. The advances within the software of biotechnological instruments not solely have constantly improved the sensitivity, selectivity, and detection vary for biosensors but in addition have concurrently unveiled new challenges and restrictions for additional enhancements.

This assessment highlights chosen facets of whole-cell biosensing of heavy metals utilizing optical transducers. We now have targeted on the progress in genetic modulation in regulatory and reporter modules of recombinant plasmids that has enabled enchancment of biosensor efficiency.

Concurrently, an try has been made to current newer platforms similar to microfluidics which have generated promising outcomes and would possibly give a brand new flip to the optical biosensing subject.

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BSA Control for Age-BSA

2221-BSA
EUR 175.00

Cotinine-BSA Conjugate

COTN15-BSA 0.5 mg
EUR 286.00

Positive control tissue section for each antibody; Based on availability INQUIRE

Control-Slides Set of 5
EUR 176.00

BSA Control for AGE-BSA

35R-AA007 10 mg
EUR 224.00
Description: BSA Control for AGE protein (BSA modified), Cat No. 30R-AA007

CEL-BSA Control

STA-302 100 µg
EUR 322.00
Description:
  • N-epsilon-(carboxyethyl) lysine (CEL) modified BSA may be used as a positive control. 100 µg at 1 mg/mL in PBS.
  • Provided at 1 mg/mL in 1X PBS

MG-BSA Control

STA-306 100 µg
EUR 322.00
Description:
  • Methylglyoxal-BSA (MG-BSA) may be used as a positive control. 100 µg at 1 mg/mL in PBS.
  • Provided at 1 mg/mL

CML-BSA Control

STA-314 100 µg
EUR 322.00
Description:
  • CML-BSA may be used as a positive control. 100 µg.
  • Provided at 1 mg/mL in 1X PBS

MDA-BSA Control

STA-333 100 µg
EUR 322.00
Description:
  • MDA-BSA (Malondialdehyde-BSA) may be used as a positive control. 100 µg.
  • Provided at 1 mg/mL in 1X PBS

Bovine Serum Albumin Biotinylated (Biotin-BSA)

BTN-BSA 5 mg
EUR 286.00

Ibrutinib drug-Bovine Serum Albumin (BSA) Conjugate

IBT15-BSA 100 ug
EUR 529.00

Phosphoserine-BSA control protein

PSER15-N 100 ug
EUR 164.00

Dinitrophenyl (DNP)-BSA protein Conjugate

AV-9330-BSA 10 mg
EUR 286.00

mPEG-BSA (Molecular Weight: 5,000-linear)

PEG-BSA-05K 100 ug
EUR 286.00

mPEG-BSA (Molecular Weight: 10,000-linear)

PEG-BSA-10K 100 ug
EUR 286.00

mPEG-BSA (Molecular Weight: 20,000-linear)

PEG-BSA-20K 100 ug
EUR 286.00

mPEG-BSA (Molecular Weight: 40,000-linear)

PEG-BSA-40K 100 ug
EUR 286.00

HNE antibody

20R-HG007 100 ug
EUR 300.00
Description: Goat polyclonal HNE antibody

4-Hydroxynonenal (HNE)-BSA protein conjugate for ELISA (in PBS)

HNE15-R 100 ug
EUR 347.00

(DRAAGQPAG)3 peptide (repeat-sequence peptide of the P. vivax circumsporozoite protein, CSP) conjugated with BSA

DRAA31-BSA 0.5 mg
EUR 529.00

(PPPPNAND)3 peptide (repeat-sequence peptide of the P. berghei circumsporozoite protein, CSP) conjugated with BSA

PPPP321-BSA 0.5 mg
EUR 529.00

(NVDP)4 peptide (minor repeat-sequence peptide of the P. falciparum circumsporozoite protein, CSP) conjugated with BSA

NVDP41-BSA 0.5 mg
EUR 529.00

(NANP)5 peptide (25-aa, repeat-sequence peptide of the P. falciparum circumsporozoite protein, CSP) conjugated with BSA

NANP51-BSA 0.5 mg
EUR 529.00

Protein Tyrosine Nitration Control (Nitrotyrosine-BSA)

STA-304 10 ?g
EUR 241.00
Description:
  • Protein Tyrosine Nitration Control (Nitrotyrosine-BSA) may be used as a positive control. 10 µg.
  • Provided at 0.1 mg/mL

Oxidized Protein Immunoblot Control (Carbonyl-BSA)

STA-309 10 ?g
EUR 241.00
Description:
  • Oxidized Protein Immunoblot Control (Carbonyl-BSA) may be used as a positive control. 10 µg.
  • Provided at 50 µg/mL

Bovine Serum Albumin (BSA) ELISA Kit

DLR-BSA-Ge-48T 48T
EUR 387.00
  • Should the Bovine Serum Albumin (BSA) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Bovine Serum Albumin (BSA) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Bovine Serum Albumin (BSA) ELISA Kit

DLR-BSA-Ge-96T 96T
EUR 494.00
  • Should the Bovine Serum Albumin (BSA) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Bovine Serum Albumin (BSA) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Bovine Serum Albumin (BSA) modified with 4-Hydroxy nonenal (4-HNE)

SPR-211A 0.05 mg
EUR 256.00
Description: Untagged synthetic panspecies 4-Hydroxynonenal BSA Conjugate for WB, ELISA. The biological activity of this protein has not yet been tested.

Bovine Serum Albumin (BSA) modified with 4-Hydroxy nonenal (4-HNE)

SPR-211B 2x0.05 mg
EUR 370.00
Description: Untagged synthetic panspecies 4-Hydroxynonenal BSA Conjugate for WB, ELISA. The biological activity of this protein has not yet been tested.

Bovine Serum Albumin (BSA) modified with 4-Hydroxy nonenal (4-HNE)

SPR-211C 4x0.05 mg
EUR 523.00
Description: Untagged synthetic panspecies 4-Hydroxynonenal BSA Conjugate for WB, ELISA. The biological activity of this protein has not yet been tested.

Bovine serum albumin (BSA) removal kit (Antibody based aff matrix; sufficient to remove 1-2 mg BSA from Bioprocessed material), 2 ml aff column

800-302-BSA 1 Kit
EUR 347.00

Bovine serum albumin (BSA) removal kit (Antibody based aff matrix; sufficient to remove 10-20 mg BSA from Bioprocessed material), 10 ml aff column

800-310-BSA 1 Kit
EUR 895.00

Bovine serum albumin (BSA) removal kit (Antibody based aff matrix; sufficient to remove 25-50 mg BSA from Bioprocessed material), 25 ml aff column

800-325-BSA 1 Kit
EUR 1450.00

General Bovine Serum Albumin (BSA) ELISA Kit

RDR-BSA-Ge-48Tests 48 Tests
EUR 551.00

General Bovine Serum Albumin (BSA) ELISA Kit

RDR-BSA-Ge-96Tests 96 Tests
EUR 766.00

General Bovine Serum Albumin (BSA) ELISA Kit

RD-BSA-Ge-48Tests 48 Tests
EUR 527.00

General Bovine Serum Albumin (BSA) ELISA Kit

RD-BSA-Ge-96Tests 96 Tests
EUR 732.00

Monoclonal Anti-4 HNE (4-HNE; 4-hydroxynonenal) IgG

HNE13-M 100 ul
EUR 482.00

4-Hydroxynonenal (HNE)-BSA protein conjugate for Western blots (in sample buffer)

HNE11-C 100 ul
EUR 286.00

4-Hydroxynonenal (HNE)-BSA protein conjugate for Western blots (in sample buffer)

HNE12-C 100 ul
EUR 286.00

Vaccigel Alum adjuvant adsorbed with Bovine Serum Albumin (BSA @1 mg/ml), Vaccine adjuvant

AV-1010-BSA 1 ml
EUR 286.00

Pre-diluted BSA (bovine serum albumin) standards (1 set) for BCA Optima Protein Assay kit

BCA-BSA-1 1 pk
EUR 164.00

Pre-diluted BSA (bovine serum albumin) standards (750 ug/ml) for BCA Optima Protein Assay kit

BCA-BSA-750 1 ml
EUR 225.00

BSA and BGG Stock standards (1 vial each @ 2 mg/ml) for BCA Optima Protein Assay kit

BSA-BGG-1 1 pk
EUR 286.00

Polyclonal HNE / Neutrophil Elastase Antibody

APS00008G 0.05mg
EUR 484.00
Description: A polyclonal antibody raised in Sheep that recognizes and binds to Human HNE / Neutrophil Elastase . This antibody is tested and proven to work in the following applications:

Human 4-HNE ELISA Kit

EHH0210 96Tests
EUR 521.00

Goat 4-HNE ELISA Kit

EGTH0210 96Tests
EUR 521.00

Bovine 4-HNE ELISA Kit

EBH0210 96Tests
EUR 521.00

Canine 4-HNE ELISA Kit

ECH0210 96Tests
EUR 521.00

Chicken 4-HNE ELISA Kit

ECKH0210 96Tests
EUR 521.00

4-HNE ELISA KIT|Human

EF006163 96 Tests
EUR 689.00

4-Hydroxynonenal (4-HNE) Antibody

abx411903-01ml 0.1 ml
EUR 509.00
  • Shipped within 1 week.

4 hydroxynonenal (HNE), >98% pure

HNE51-1 1 mg
EUR 202.00

4 hydroxynonenal (HNE), >98% pure

HNE51-5 5 mg
EUR 651.00

Rat 4-HNE ELISA Kit

ERH0210 96Tests
EUR 521.00

Sheep 4-HNE ELISA Kit

ESH0210 96Tests
EUR 521.00

Rabbit 4-HNE ELISA Kit

ERTH0210 96Tests
EUR 521.00

Mouse 4-HNE ELISA Kit

EMH0210 96Tests
EUR 521.00

Monkey 4-HNE ELISA Kit

EMKH0210 96Tests
EUR 521.00

Porcine 4-HNE ELISA Kit

EPH0210 96Tests
EUR 521.00

anti-4-HNE (HNEJ-2)

LF-MA90010 20 ug
EUR 360.00
Description: Mouse monoclonal to 4-HNE

anti-4-HNE (HNEJ-2)

LF-MA90011 100 ug
EUR 891.00
Description: Mouse monoclonal to 4-HNE

Malondialdehyde (MDA)-BSA Conjugate positive control for Western/ELISA

MDA35-N-100 100 ug
EUR 286.00

Pre-diluted BSA (bovine serum albumin) standards (250, 125, 62.5, 31.25, and 0.0 ug/ml) for BCA Optima Protein Assay kit

BCA-BSA-2 1 pk
EUR 164.00

Albumin (Human, Mouse, rat, bovine and others) removal kit (synthetic dye based matrix; sufficient to remove 20-40 mg BSA from Bioprocessed material), 2 ml aff column

800-200-BSA 1 kit
EUR 286.00

Albumin (Human, Mouse, rat, bovine and others) removal kit (synthetic dye based matrix; sufficient to remove 50-100 mg BSA from Bioprocessed material), 5 ml aff column

800-205-BSA 1 kit
EUR 773.00

Albumin (Human, Mouse, rat, bovine and others) removal kit (synthetic dye based matrix; sufficient to remove 250-500 mg BSA from Bioprocessed material), 25 ml aff column

800-225-BSA 1 kit
EUR 2425.00

Rat 4-Hydroxynonenal(HNE)ELISA Kit

CSB-EQ027232RA-24T 1 plate of 24 wells
EUR 165.00
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativecompetitive ELISA kit for measuring Rat 4-Hydroxynonenal (HNE) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat 4-Hydroxynonenal(HNE)ELISA Kit

1-CSB-EQ027232RA
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 0
  • 1
  • 2
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativecompetitive ELISA kit for measuring Rat 4-Hydroxynonenal(HNE) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

4-Hydroxynonenal (4-HNE) ELISA Kit

abx257639-96tests 96 tests
EUR 668.00
  • Shipped within 5-12 working days.

Guinea Pig 4-HNE ELISA Kit

EGH0210 96Tests
EUR 521.00

4-Hydroxynonenal (4-HNE) ELISA Kit

E4645-100
EUR 865.00

Mouse 4-Hydroxynonenal (HNE)ELISA Kit

CSB-E13412m-24T 1 plate of 24 wells
EUR 165.00
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Mouse 4-Hydroxynonenal (HNE) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse 4-Hydroxynonenal (HNE)ELISA Kit

1-CSB-E13412m
  • EUR 900.00
  • EUR 5476.00
  • EUR 2900.00
  • 0
  • 1
  • 2
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Mouse 4-Hydroxynonenal (HNE) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human 4-Hydroxynonenal (HNE)ELISA Kit

CSB-E16214h-24T 1 plate of 24 wells
EUR 165.00
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativecompetitive ELISA kit for measuring Human 4-Hydroxynonenal (HNE) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human 4-Hydroxynonenal (HNE)ELISA Kit

1-CSB-E16214h
  • EUR 804.00
  • EUR 5099.00
  • EUR 2704.00
  • 0
  • 1
  • 2
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativecompetitive ELISA kit for measuring Human 4-Hydroxynonenal (HNE) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rabbit Anti-4 hydroxynonenal (HNE) antiserum

HNE11-S 100 ul
EUR 457.00

OxiSelect HNE Adduct Competitive ELISA Kit

STA-838 96 assays
EUR 798.00
Description: 4-hydroxynonenal (4-HNE or HNE) is a well known by-product of lipid peroxidation and is widely accepted as a stable marker for oxidative stress. Our OxiSelect HNE Adduct Competitive ELISA Kit measures the formation of HNE adducts to any protein residue using a competitive ELISA format.

OxiSelect HNE Adduct Competitive ELISA Kit

STA-838-5 5 x 96 assays
EUR 3240.00
Description: 4-hydroxynonenal (4-HNE or HNE) is a well known by-product of lipid peroxidation and is widely accepted as a stable marker for oxidative stress. Our OxiSelect HNE Adduct Competitive ELISA Kit measures the formation of HNE adducts to any protein residue using a competitive ELISA format.

ELISA kit for 4-HNE (4-Hydroxynonenal)

E-EL-0128 1 plate of 96 wells
EUR 377.00
  • Gentaur's 4-HNE ELISA kit utilizes the Competitive-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with 4-HNE. During the reaction, 4-HNE in the sample or standard competes with a fixed amount of 4-HNE on the solid pha
  • Show more
Description: A competitive ELISA kit for quantitative measurement of 4-HNE (4-Hydroxynonenal) in samples from Serum, Plasma, Cell supernatant

Mouse 4-Hydroxynonenal (4-HNE) ELISA Kit

abx257660-96tests 96 tests
EUR 754.00
  • Shipped within 5-12 working days.

Human 4-Hydroxynonenal (4-HNE) ELISA Kit

abx251411-96tests 96 tests
EUR 754.00
  • Shipped within 5-12 working days.

Human 4-HNE(4-Hydroxynonenal) ELISA Kit

EH2080 96T
EUR 524.10
  • Detection range: 31.25-2000 pg/ml
  • Alias: 4-HNE(4-Hydroxynonenal)/HNE/4 HNE
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75 pg/ml

Goat Anti-4 hydroxynonenal (HNE) antiserum #2

HNE12-S 100 ul
EUR 457.00

Mouse 4-HNE(4-Hydroxynonenal) ELISA Kit

EM1583 96T
EUR 524.10
  • Detection range: 31.25-2000 pg/ml
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Mus ;Sensitivity: 18.75pg/ml

Rat 4-HNE(4-Hydroxynonenal) ELISA Kit

ER1587 96T
EUR 524.10
  • Detection range: 31.25-2000 pg/ml
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Rattus;Sensitivity: 18.75 pg/ml

Goat Anti-4-Hydroxynonenal (HNE) Polyclonal Antibody

STA-034 100 µg
EUR 664.00
Description: Goat Anti-4-hydroxynonenal Polyclonal Antibody is Affinity purified and suitable for Western blot or ELISA. Suitable for use with any species. 100 µg.

Rabbit Anti-4-Hydroxynonenal (HNE) Polyclonal Antibody

STA-035 100 µg
EUR 664.00
Description: Rabbit Anti-4-hydroxynonenal Polyclonal Antibody is Affinity purified and suitable for Western blot or ELISA. Suitable for use with any species. 100 µg.

BSA

31C-CH0114 50 mg
EUR 133.00
Description: Bovine Serum Albumin for use in the research laboratory

Testosterone 3 BSA Protein (BSA)

abx060856-1mg 1 mg
EUR 578.00
  • Shipped within 5-10 working days.

Ibrutinib drug-Human Serum Albumin Conjugate

IBT16-BSA 100 ug
EUR 529.00

Mouse (mrl/lpr) serum containing autoantibodies to HNE

HNE31-M 100 ul
EUR 482.00

OxiSelect HNE Adduct Competitive ELISA Kit, Trial Size

STA-838-T 32 assays
EUR 421.00
Description: 4-hydroxynonenal (4-HNE or HNE) is a well known by-product of lipid peroxidation and is widely accepted as a stable marker for oxidative stress. Our OxiSelect HNE Adduct Competitive ELISA Kit measures the formation of HNE adducts to any protein residue using a competitive ELISA format.

Control siRNA Vector (pGB-control)

9500C-20
EUR 338.00

Histamine [G-BSA] (G-G-BSA)

DAG3327 1mg
EUR 1234.00

Cyclic citrullinated peptide-BSA(CCP-BSA)

E64I00802 100ug
EUR 343.00

AGE-BSA

2221-10
EUR 370.00

AGE-BSA

2221-50 Ask for price

BSA antibody

20R-1871 100 ug
EUR 673.00
Description: Rabbit polyclonal BSA antibody

BSA antibody

20R-AR042 20 mg
EUR 327.00
Description: Rabbit polyclonal BSA antibody

BSA antibody

70R-12462 100 ug
EUR 460.00
Description: Rabbit polyclonal BSA antibody

BSA antibody

70-BC67 1 mg
EUR 191.00
Description: Affinity purified Chicken polyclonal BSA antibody

BSA antibody

70C-CR1016GAP 1 mg
EUR 430.00
Description: Affinity purified Goat polyclonal BSA antibody

LSD-BSA

65R-1007 1 mg
EUR 743.00
Description: LSD-BSA Conjugated Hapten

BSA Antibody

48061-100ul 100ul
EUR 333.00

BSA Antibody

48061-50ul 50ul
EUR 239.00

BSA Antibody

35643-100ul 100ul
EUR 252.00

BSA antibody

10R-1795 100 ul
EUR 435.00
Description: Mouse monoclonal BSA antibody

BSA antibody

10R-10573 100 ul
EUR 349.00
Description: Mouse monoclonal BSA antibody

BSA antibody

10-1911 200 ul
EUR 543.00
Description: Mouse monoclonal BSA antibody

BSA antibody

10R-A139B 500 µg
EUR 771.00
Description: Mouse monoclonal BSA antibody

BSA Antibody

5998-100
EUR 354.00

BSA Antibody

5998-30T
EUR 146.00

BSA Antibody

1-CSB-PA000390
  • EUR 222.00
  • EUR 195.00
  • 0
  • 1
  • Form: Liquid
  • Buffer: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Affinity purification
Description: A polyclonal antibody against BSA. Recognizes BSA from Cow. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1:2000-5000

Paromomycin [BSA]

DAG-P2529 1mg
EUR 780.00

Ciclosporin [BSA]

DAG-WZ017A 1 mg
EUR 1040.00

Acetaminophen [BSA]

DAG2957 0.5mg
EUR 780.00

Chloramphenicol [BSA]

DAG2974 1mg
EUR 584.00

Gentamycin [BSA]

DAG2993 1mg
EUR 715.00

PCP [BSA]

DAG3015 1 mg
EUR 715.00

estosterone [BSA]

DAG3023 1mg
EUR 910.00

Digoxin [BSA]

DAG3043 0.5ml
EUR 715.00

Methamphetamine [BSA]

DAG3101 1mg
EUR 897.00

Secobarbital [BSA]

DAG3102 1 mg
EUR 780.00

Oxazepam [BSA]

DAG3106 1 mg
EUR 897.00

Carisoprodol [BSA]

DAG3107 1 mg
EUR 780.00

Biotin [BSA]

DAG3197 1mg
EUR 481.00

Acrolein [BSA]

DAG3266 100ug
EUR 1040.00

Agmatine [BSA]

DAG3267 100ug
EUR 845.00

Carnosine [BSA]

DAG3279 1mg
EUR 1105.00

Diclofenac [BSA]

DAG3299 1mg
EUR 1105.00

Dopamine [BSA]

DAG3302 1mg
EUR 1105.00

Adrenaline [BSA]

DAG3306 1mg
EUR 1364.00

Glycine [BSA]

DAG3313 250ug
EUR 715.00

Glyoxal [BSA]

DAG3314 250ug
EUR 780.00

Ibuprofen [BSA]

DAG3353 1mg
EUR 1221.00

Malondialdehyde [BSA]

DAG3366 1mg
EUR 1170.00

Naproxen [BSA]

DAG3370 250ug
EUR 585.00

Nicotinamide [BSA]

DAG3371 1mg
EUR 845.00

Pyridoxal [BSA]

DAG3394 1mg
EUR 1235.00

Pyridoxine [BSA]

DAG3395 1mg
EUR 1235.00

Riboflavin [BSA]

DAG3399 1mg
EUR 845.00

Rotenone [BSA]

DAG3400 mg
EUR 780.00

Buprenorphine [BSA]

DAG394 1mg
EUR 780.00

Propoxyphene [BSA]

DAG397 1 mg
EUR 1105.00

Fentanyl [BSA]

DAG398 1 mg
EUR 697.00

Tramadol [BSA]

DAG399 1mg
EUR 1222.00

Ketamine [BSA]

DAG400 1mg
EUR 715.00

Cotinine [BSA]

DAG401 1mg
EUR 780.00

THC [BSA]

DAG406 1mg
EUR 715.00

Phenobarbital [BSA]

DAG421 1mg
EUR 845.00

Theophylline [BSA]

DAG426 10mg
EUR 780.00

Amoxicillin [BSA]

DAG4461 0.5mg
EUR 780.00

Ampicillin [BSA]

DAG4462 0.5mg
EUR 780.00

Apramycin [BSA]

DAG4463 0.5mg
EUR 780.00

Bacitracin [BSA]

DAG4464 1mg
EUR 780.00

Cloxacillin [BSA]

DAG4467 0.5mg
EUR 780.00

Neomycin [BSA]

DAG4470 0.5ml
EUR 780.00

Streptomycin [BSA]

DAG4472 0.5ml
EUR 780.00

Melamine [BSA]

DAG4476 1mg
EUR 780.00

Ractopamine [BSA]

DAGA-001B 1mg
EUR 715.00

Salbutamol [BSA]

DAGA-002B 1mg
EUR 780.00

Clenbuterol [BSA]

DAGA-003B 1mg
EUR 780.00

Pb2+ [BSA]

DAGA-005B 1mg
EUR 1105.00

Cd2+ [BSA]

DAGA-006B 1mg
EUR 897.00

Hg2+ [BSA]

DAGA-007B 1mg
EUR 897.00

Cu2+ [BSA]

DAGA-008B 1mg
EUR 780.00

Ochratoxin [BSA]

DAGA-012B 1mg
EUR 780.00

Fumonisin [BSA]

DAGA-014B 1mg
EUR 780.00

Deoxynivalenol [BSA]

DAGA-016B 1mg
EUR 715.00

Sterigmatocystin [BSA]

DAGA-017B 1mg
EUR 845.00

Methyltestosterone [BSA]

DAGA-020B 1mg
EUR 780.00

Medroxyprogesterone [BSA]

DAGA-021B 1mg
EUR 780.00

Diethylstilbestrol [BSA]

DAGA-022B 1mg
EUR 714.00

Hexoestrolum [BSA]

DAGA-023B 1mg
EUR 702.00

Hydrocortisone [BSA]

DAGA-024B 1mg
EUR 780.00

 

Immune evasion in renal cell carcinoma: biology, scientific translation, future instructions

 

Focused therapies and immune checkpoint inhibitors have superior the therapy panorama of Renal Cell Carcinoma (RCC) during the last decade. Whereas checkpoint inhibitors have demonstrated survival profit and are at present accredited within the front-line and second-line settings, major and secondary resistance is widespread.

A complete understanding of the mechanisms of immune evasion in RCC is due to this fact crucial to the event of efficient mixture therapy methods. This text opinions the present understanding of the completely different, but coordinated, mechanisms adopted by RCC cells to evade immune killing; summarizes varied facets of scientific translation thus far, together with the at present registered RCC scientific trials exploring brokers together with checkpoint inhibitors; and offers views on the present panorama and future instructions for the sphere.

 

Eukaryotic cell biology is temporally coordinated to help the energetic calls for of protein homeostasis

Yeast physiology is temporally regulated, this turns into obvious below nutrient-limited situations and ends in respiratory oscillations (YROs). YROs share options with circadian rhythms and work together with, however are impartial of, the cell division cycle. Right here, we present that YROs minimise power expenditure by limiting protein synthesis till enough sources are saved, whereas sustaining osmotic homeostasis and protein high quality management.

Though nutrient provide is fixed, cells sequester and retailer metabolic sources through elevated transport, autophagy and biomolecular condensation. Replete shops set off elevated H+ export which stimulates TORC1 and liberates proteasomes, ribosomes, chaperones and metabolic enzymes from non-membrane certain compartments. This facilitates translational bursting, liquidation of storage carbohydrates, elevated ATP turnover, and the export of osmolytes.

We suggest that dynamic regulation of ion transport and metabolic plasticity are required to keep up osmotic and protein homeostasis throughout remodelling of eukaryotic proteomes, and that bioenergetic constraints chosen for temporal organisation that promotes oscillatory behaviour.

Dysregulation of membership cell biology in idiopathic pulmonary fibrosis

 

Idiopathic pulmonary fibrosis (IPF) is a progressive, persistent fibrotic lung illness with an irreversible decline of lung perform. “Bronchiolization”, characterised by ectopic look of airway epithelial cells within the alveolar areas, is without doubt one of the attribute options within the IPF lung.

Primarily based on the data that membership cells are the foremost epithelial secretory cells in human small airways, and their main secretory product uteroglobin (SCGB1A1) is considerably elevated in each serum and epithelial lining fluid of IPF lung, we hypothesize that human airway membership cells contribute to the pathogenesis of IPF.

By assessing the transcriptomes of the only cells from human lung of management donors and IPF sufferers, we recognized two SCGB1A1+ membership cell subpopulations, extremely expressing MUC5B, a major genetic threat issue strongly related with IPF, and SCGB3A2, a marker heterogeneously expressed within the membership cells, respectively. Apparently, the mobile proportion of SCGB1A1+MUC5B+ membership cells was considerably elevated in IPF sufferers, and this membership cell subpopulation extremely expressed genes associated to mucous manufacturing and immune cell chemotaxis.

In distinction, although the mobile proportion didn’t change, the molecular phenotype of the SCGB1A1+SCGB3A2high membership cell subpopulation was considerably altered in IPF lung, with elevated expression of mucins, cytokine and extracellular matrix genes. The one cell transcriptomic evaluation reveals the mobile and molecular heterogeneity of membership cells, and supply novel insights into the organic features of membership cells within the pathogenesis of IPF.

 

Metabolic and Redox regulation of cardiovascular stem cell biology and pathology

Significance: Cardiovascular stem cells are essential for regeneration and restore of broken tissue. Current Advances: Pluripotent stem cells have a novel metabolism, which is adopted to their energetic and biosynthetic demand as quickly proliferating cells. Stem cell differentiation requires an distinctive metabolic flexibility permitting for metabolic reworking between glycolysis and oxidative phosphorylation.
Essential points: Respiration is related to the technology of reactive oxygen species (ROS) by the mitochondrial respiratory chain. But in addition the membrane-bound protein nicotinamide adenine dinucleotide phosphate oxidase (NADPH oxidase, NOX) contributes to ROS ranges. ROS performs a major position in stem cell differentiation and tissue renewal but in addition trigger senescence and contribute to tissue growing older.
Future instructions: For utilization of stem cells in therapeutic approaches, a deep understanding of the molecular mechanisms how metabolism and the mobile redox state regulates stem cell differentiation is required. Modulating the redox state of stem cells utilizing antioxidative brokers could also be appropriate to boost exercise of endothelial progenitor cells.

Thiol switches in membrane proteins – Additionalcellular redox regulation in cell biology

Redox-mediated sign transduction is determined by the enzymatic manufacturing of second messengers similar to hydrogen peroxide, nitric oxide and hydrogen sulfite, in addition to particular, reversible redox modifications of cysteine-residues in proteins.
So-called thiol switches induce as an illustration conformational modifications in particular proteins that regulate mobile pathways e.g., cell metabolism, proliferation, migration, gene expression and irritation.
Discount, oxidation and disulfide isomerization are managed by oxidoreductases of the thioredoxin household, together with thioredoxins, glutaredoxins, peroxiredoxins and protein dsisulfide isomerases. These proteins are situated in several mobile compartments, work together with substrates and catalyze particular reactions.
Apparently, a few of these proteins are launched by cells. Their extracellular features and usually extracellular redox management have been broadly underestimated. Right here, we give an perception into extracellular redox signaling, extracellular thiol switches and their regulation by secreted oxidoreductases and thiol-isomerases, a subject whose significance has been scarcely studied up to now, possible attributable to methodological limitations.
We concentrate on the secreted redox proteins and characterised thiol switches within the ectodomains of membrane proteins, similar to integrins and the metalloprotease ADAM17, that are among the many best-characterized proteins and talk about their underlying mechanisms and organic implications.

pAAV-RC9 vector

PVT12073 2 ug
EUR 524.00

pAAV-DJ vector

PVT12151 2 ug
EUR 438.00

pAAV-DJ Vector

VPK-420-DJ 10 µg
EUR 647.00
Description: The pAAV-DJ vector contains the rep and cap genes required to generated recombinant AAV of serotype DJ. Co-transfect with other packaging plasmids and an expression vector into 293 cells for AAV-DJ packaging.

pAAV-RC1 Vector

VPK-421 10 µg
EUR 647.00
Description: The pAAV-RC1 vector contains the rep and cap genes required to generated recombinant AAV of serotype 1. Co-transfect with other packaging plasmids and an expression vector into 293 cells for AAV-1 packaging.

pAAV-RC3 Vector

VPK-423 10 µg
EUR 647.00
Description: The pAAV-RC3 vector contains the rep and cap genes required to generated recombinant AAV of serotype 3. Co-transfect with other packaging plasmids and an expression vector into 293 cells for AAV-3 packaging.

pAAV-RC4 Vector

VPK-424 10 µg
EUR 647.00
Description: The pAAV-RC4 vector contains the rep and cap genes required to generated recombinant AAV of serotype 4. Co-transfect with other packaging plasmids and an expression vector into 293 cells for AAV-4 packaging.

pAAV-RC5 Vector

VPK-425 10 µg
EUR 647.00
Description: The pAAV-RC5 vector contains the rep and cap genes required to generated recombinant AAV of serotype 5. Co-transfect with other packaging plasmids and an expression vector into 293 cells for AAV-5 packaging.

pAAV-RC6 Vector

VPK-426 10 µg
EUR 647.00
Description: The pAAV-RC6 vector contains the rep and cap genes required to generated recombinant AAV of serotype 6. Co-transfect with other packaging plasmids and an expression vector into 293 cells for AAV-6 packaging.

pAAV-RC6

PVT14647 2 ug
EUR 703.00

pAAV- RC

PVT2103 2 ug
EUR 241.00

pAAV-GFP Control Vector

AAV-400 10 µg
EUR 566.00
Description: Use this control vector to co-transfect along with AAV packaging vectors to produce a recombinant AAV control.

pAAV-Cre Control Vector

AAV-401 10 µg
EUR 566.00
Description: Use this control vector to co-transfect along with AAV packaging vectors to produce a recombinant AAV control.

pAAV-LacZ Control Vector

AAV-402 10 µg
EUR 566.00
Description: Use this control vector to co-transfect along with AAV packaging vectors to produce a recombinant AAV control.

pAAV-MCS Expression Vector

VPK-410 10 µg
EUR 647.00
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-DJ/8 Vector

VPK-420-DJ-8 10 µg
EUR 647.00
Description: The pAAV-DJ/8 vector contains the rep and cap genes required to generated recombinant AAV of serotype DJ/8. Co-transfect with other packaging plasmids and an expression vector into 293 cells for AAV-DJ/8 packaging.

pAAV- IRES- ZsGreen1

PVT11044 2 ug
EUR 301.00

pAAV- ZsGreen1- shRNA

PVT11045 2 ug
EUR 370.00

pAAV-fNPY-GFP

PVT14636 2 ug
EUR 599.00

pAAV-RSV-SpCas9

PVT17629 2 ug
EUR 300.00

pAAV-CAG-GFP

PVT17666 2 ug
EUR 341.00

pAAV- MCS Plasmid

PVT2102 2 ug
EUR 241.00

pAAV-MCS Promoterless Expression Vector

VPK-411 10 µg
EUR 647.00
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-IRES-Puro Expression Vector

VPK-415 10 µg
EUR 647.00
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-IRES-Neo Expression Vector

VPK-416 10 µg
EUR 647.00
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-IRES-Hygro Expression Vector

VPK-417 10 µg
EUR 647.00
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-IRES-GFP Expression Vector

VPK-418 10 µg
EUR 647.00
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-IRES-Bsd Expression Vector

VPK-419 10 µg
EUR 647.00
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-EF1a-DIO-mCherry

PVT17841 2 ug
EUR 300.00

pAAV- IRES- hrGFP Plasmid

PVT2104 2 ug
EUR 266.00

Human Topoisomerase I

TG2005H-RC2 500 units
EUR 448.00

pAAV- CMV- mCherry- U6- sgRNA

PVT11046 2 ug
EUR 301.00

pAAV-hSyn-hChR2(H134R)-mCherry

PVT19026 2 ug
EUR 258.00

pAAV-hSyn-eNpHR 3.0-EYFP

PVT19063 2 ug
EUR 258.00

pAAV-EF1a-DIO-hM3D(Gq)-mCherry

PVT17847 2 ug
EUR 300.00

pAAV-MCS-Ppargc1a-m-FLAG-HA

PVT18341 2 ug
EUR 300.00

pVL1392 Vector

ABP-BVP-10001 5 ug Ask for price
    • Product line: Sapphire Baculovirus
    • Brand: Transfer Plasmids

pVL1393 Vector

ABP-BVP-10002 5 ug Ask for price
    • Product line: Sapphire Baculovirus
    • Brand: Transfer Plasmids

pORB Vector

ABP-BVP-10003 5 ug Ask for price
    • Product line: Sapphire Baculovirus
    • Brand: Transfer Plasmids

pAcSec1 Vector

ABP-BVP-10004 5 ug Ask for price
    • Product line: Sapphire Baculovirus
    • Brand: Transfer Plasmids

pAcIRES Vector

ABP-BVP-10005 5 ug Ask for price
    • Product line: Sapphire Baculovirus
    • Brand: Transfer Plasmids

pEE14.4 vector

PVT11901 2 ug
EUR 1036.00

pENTR223.1 vector

PVT11990 2 ug
EUR 352.00

pUB_smFLAG_KDM5B_MS2 vector

PVT11991 2 ug
EUR 352.00

ER2738 vector

PVT11993 2 ug
EUR 352.00

pFLPo vector

PVT12063 2 ug
EUR 352.00

pREDKI vector

PVT12064 2 ug
EUR 352.00

pREDCas9 vector

PVT12065 2 ug
EUR 352.00

PWUR790 vector

PVT12066 2 ug
EUR 352.00

xCas9 vector

PVT12068 2 ug
EUR 352.00

sgRNA vector

PVT12071 2 ug
EUR 352.00

PY094 vector

PVT12150 2 ug
EUR 352.00

PY094 vector

PVT12150-1 2 ug
EUR 352.00

pRGEB31 vector

PVT12152 2 ug
EUR 352.00

pSET152 vector

PVT3395 2 ug
EUR 376.00

pYLEX1 - Expression Vector

FYY203-5MG 5mg Ask for price

pYLSC1- Secretion Vector

FYY204-5MG 5mg Ask for price

pMRNAxp mRNAExpress Vector

MR000PA-1 10 ug
EUR 900.00
  • Category: Stem Cell Products

pMXs Retroviral Vector

RTV-010 10 µg
EUR 624.00
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMYs Retroviral Vector

RTV-020 10 µg
EUR 624.00
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pMZs Retroviral Vector

RTV-030 10 µg
EUR 624.00
Description: Use this construct to clone your gene for downstream recombinant retroviral packaging

pENTR223-ATP5PO vector

PVT11685 2 ug
EUR 304.00

pENTR223- LC25A10 vector

PVT11686 2 ug
EUR 304.00

pENTR223-RSU1 vector

PVT11687 2 ug
EUR 304.00

pENTR223-CCDC24 vector

PVT11688 2 ug
EUR 304.00

pENTR223-BAT2L vector

PVT11689 2 ug
EUR 304.00

pENTR223-RSPH14 vector

PVT11690 2 ug
EUR 304.00

pENTR223-ABHD5 vector

PVT11691 2 ug
EUR 304.00

pENTR223-NONO vector

PVT11692 2 ug
EUR 304.00

pENTR223-MYOZ1 vector

PVT11693 2 ug
EUR 304.00

pENTR223-STX5 vector

PVT11694 2 ug
EUR 304.00

pENTR223-GK5 vector

PVT11695 2 ug
EUR 304.00

pENTR223-PIGC vector

PVT11696 2 ug
EUR 304.00

pENTR223-FCGR3A vector

PVT11697 2 ug
EUR 304.00

pENTR223-ANXA8L1 vector

PVT11698 2 ug
EUR 304.00

pENTR223-CDK5 vector

PVT11699 2 ug
EUR 304.00

pENTR223-ERP27 vector

PVT11700 2 ug
EUR 304.00

pENTR223-ZDHHC16 vector

PVT11701 2 ug
EUR 304.00

pENTR223-DFNA5 vector

PVT11702 2 ug
EUR 304.00

pENTR223-MPPED2 vector

PVT11703 2 ug
EUR 304.00

pENTR223-NIFK vector

PVT11704 2 ug
EUR 304.00

pENTR223-KCTD17 vector

PVT11705 2 ug
EUR 304.00

pENTR223-CEP170P1 vector

PVT11706 2 ug
EUR 304.00

pENTR223-SCML4 vector

PVT11707 2 ug
EUR 304.00

pENTR223-CLEC18C vector

PVT11708 2 ug
EUR 304.00

pENTR223-HSD17B11 vector

PVT11709 2 ug
EUR 304.00

pENTR223-UBXN1 vector

PVT11710 2 ug
EUR 304.00

pENTR223-MRPL4 vector

PVT11714 2 ug
EUR 304.00

pENTR223-DECR2 vector

PVT11715 2 ug
EUR 304.00

pENTR223-GNB3 vector

PVT11716 2 ug
EUR 304.00

pENTR223-FAM118B vector

PVT11717 2 ug
EUR 304.00

pENTR223-EIF2S2 vector

PVT11718 2 ug
EUR 304.00

pENTR223-HDAC11 vector

PVT11720 2 ug
EUR 304.00

pENTR223-RDH11 vector

PVT11721 2 ug
EUR 304.00

pENTR223-GNB1L vector

PVT11722 2 ug
EUR 304.00

pENTR223-BCL2L14 vector

PVT11723 2 ug
EUR 304.00

pENTR223-RPLP0 vector

PVT11724 2 ug
EUR 304.00

pENTR223-RALYL vector

PVT11725 2 ug
EUR 304.00

pENTR223-GPM6A vector

PVT11726 2 ug
EUR 304.00

pENTR223-BLVRA vector

PVT11727 2 ug
EUR 304.00

pENTR223-CDCP1 vector

PVT11729 2 ug
EUR 304.00

pENTR223-BTN2A2 vector

PVT11730 2 ug
EUR 304.00

pENTR223-MAX vector

PVT11731 2 ug
EUR 304.00

pENTR223-CRAT vector

PVT11732 2 ug
EUR 304.00

pENTR223-FKBPL vector

PVT11733 2 ug
EUR 304.00

pENTR223-SIAT7E vector

PVT11736 2 ug
EUR 304.00

pENTR223-AATF vector

PVT11737 2 ug
EUR 304.00

pENTR223-PEF1 vector

PVT11742 2 ug
EUR 304.00

pENTR223-INKA2 vector

PVT11743 2 ug
EUR 304.00

pENTR223-C5AR1 vector

PVT11745 2 ug
EUR 304.00

pENTR223-UBE2V1 vector

PVT11752 2 ug
EUR 304.00

pENTR223-USP47 vector

PVT11753 2 ug
EUR 304.00

pENTR223-MCFD2 vector

PVT11754 2 ug
EUR 304.00

pENTR223-PFDN2 vector

PVT11755 2 ug
EUR 304.00

pENTR223-HSP90AB1 vector

PVT11756 2 ug
EUR 304.00

pENTR223-AFAP1 vector

PVT11757 2 ug
EUR 304.00

pENTR223-STAT5A vector

PVT11761 2 ug
EUR 304.00

pENTR223-PRDM4 vector

PVT11762 2 ug
EUR 304.00

pENTR223-NGEF vector

PVT11763 2 ug
EUR 304.00

pENTR223-MAP7 vector

PVT11764 2 ug
EUR 304.00

pENTR223-EXT1 vector

PVT11765 2 ug
EUR 304.00

pENTR223-CARS vector

PVT11766 2 ug
EUR 304.00

pENTR223-STAT1 vector

PVT11767 2 ug
EUR 304.00

pENTR223-TMEM108 vector

PVT11768 2 ug
EUR 304.00

pENTR223-WDR1 vector

PVT11769 2 ug
EUR 304.00

pENTR223-POMT2 vector

PVT11770 2 ug
EUR 304.00

pENTR223-CLPB vector

PVT11771 2 ug
EUR 304.00

pENTR223-KIF1B vector

PVT11772 2 ug
EUR 304.00

pENTR223-MSTO1 vector

PVT11773 2 ug
EUR 304.00

pENTR223-DVL3 vector

PVT11775 2 ug
EUR 304.00

pENTR223-IGHM vector

PVT11776 2 ug
EUR 304.00

pENTR223-CFB vector

PVT11779 2 ug
EUR 304.00

pENTR223-TTC14 vector

PVT11780 2 ug
EUR 304.00

pENTR223-USHBP1 vector

PVT11781 2 ug
EUR 304.00

pENTR223-ATG7 vector

PVT11783 2 ug
EUR 304.00

pENTR223-CPT1A vector

PVT11785 2 ug
EUR 304.00

pENTR223-YY1AP1 vector

PVT11786 2 ug
EUR 304.00

pENTR223-PFKM vector

PVT11787 2 ug
EUR 304.00

pENTR223-FES vector

PVT11789 2 ug
EUR 304.00

pENTR223-PIGQ vector

PVT11790 2 ug
EUR 304.00

pENTR223-RARS vector

PVT11791 2 ug
EUR 304.00

pENTR223-MAN1B1 vector

PVT11792 2 ug
EUR 304.00

pENTR223-HSPA2 vector

PVT11793 2 ug
EUR 304.00

pENTR223-ARAF vector

PVT11794 2 ug
EUR 304.00

pENTR223-PIAS3 vector

PVT11795 2 ug
EUR 304.00

pENTR223-WBP11 vector

PVT11797 2 ug
EUR 304.00

pENTR223-LGALS3BP vector

PVT11798 2 ug
EUR 304.00

pENTR223-GTF3C2 vector

PVT11799 2 ug
EUR 304.00

pENTR223-KLHL12 vector

PVT11800 2 ug
EUR 304.00

pENTR223-MEN1 vector

PVT11801 2 ug
EUR 304.00

pENTR223-PCM1 vector

PVT11802 2 ug
EUR 304.00

pENTR223-SLC43A1 vector

PVT11803 2 ug
EUR 304.00

pENTR223-NRBP1 vector

PVT11804 2 ug
EUR 304.00

pENTR223-NAE1 vector

PVT11805 2 ug
EUR 304.00

pENTR223-CCDC28A vector

PVT11806 2 ug
EUR 304.00

pENTR223-UBC vector

PVT11807 2 ug
EUR 304.00

pENTR223-PFN1 vector

PVT11808 2 ug
EUR 304.00

pENTR223-TMEM239 vector

PVT11809 2 ug
EUR 304.00

pENTR223-CDH16 vector

PVT11810 2 ug
EUR 304.00

pENTR223-PMCH vector

PVT11811 2 ug
EUR 304.00

pENTR223-WDR63 vector

PVT11812 2 ug
EUR 304.00

pENTR223-PLA2G16 vector

PVT11813 2 ug
EUR 304.00

pENTR223-CEP290 vector

PVT11814 2 ug
EUR 304.00

pENTR223-RARRES2 vector

PVT11815 2 ug
EUR 304.00

pENTR223-ATG12 vector

PVT11816 2 ug
EUR 304.00

pENTR223-ERG28 vector

PVT11817 2 ug
EUR 304.00

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