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Metabolic and Redox regulation of cardiovascular stem cell biology and pathology

Current advances in artificial biology-enabled and pure whole-cell optical biosensing of heavy metals

 

A lot of scientific works have been printed on whole-cell heavy steel biosensing primarily based on optical transduction. The advances within the software of biotechnological instruments not solely have constantly improved the sensitivity, selectivity, and detection vary for biosensors but in addition have concurrently unveiled new challenges and restrictions for additional enhancements.

This assessment highlights chosen facets of whole-cell biosensing of heavy metals utilizing optical transducers. We now have targeted on the progress in genetic modulation in regulatory and reporter modules of recombinant plasmids that has enabled enchancment of biosensor efficiency.

Concurrently, an try has been made to current newer platforms similar to microfluidics which have generated promising outcomes and would possibly give a brand new flip to the optical biosensing subject.

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denguenaweb

BSA Control for AGE-BSA

35R-AA007 10 mg Ask for price
Description: BSA Control for AGE protein (BSA modified), Cat No. 30R-AA007

MG-BSA Control

STA-306 100 µg
EUR 386.4
Description:
  • Methylglyoxal-BSA (MG-BSA) may be used as a positive control. 100 µg at 1 mg/mL in PBS.
  • Provided at 1 mg/mL

CEL-BSA Control

STA-302 100 µg
EUR 245

CML-BSA Control

STA-314 100 µg
EUR 386.4
Description:
  • CML-BSA may be used as a positive control. 100 µg.
  • Provided at 1 mg/mL in 1X PBS

MDA-BSA Control

STA-333 100 µg
EUR 245

Phosphoserine-BSA control protein

PSER15-N 100 ug
EUR 196.8

4-Hydroxynonenal (HNE)-BSA protein conjugate for ELISA (in PBS)

HNE15-R 100 ug
EUR 416.4

Malondialdehyde (MDA)-BSA Conjugate positive control for Western/ELISA

MDA35-N-100 100 ug
EUR 343.2

Oxidized Protein Immunoblot Control (Carbonyl-BSA)

STA-309 10 ?g
EUR 170

Protein Tyrosine Nitration Control (Nitrotyrosine-BSA)

STA-304 10 ?g
EUR 289.2
Description:
  • Protein Tyrosine Nitration Control (Nitrotyrosine-BSA) may be used as a positive control. 10 µg.
  • Provided at 0.1 mg/mL

4-Hydroxynonenal (HNE)-BSA protein conjugate for Western blots (in sample buffer)

HNE11-C 100 ul
EUR 343.2

4-Hydroxynonenal (HNE)-BSA protein conjugate for Western blots (in sample buffer)

HNE12-C 100 ul
EUR 343.2

Rabbit Anti-Bovine Serum Albumin (BSA) IgG positive control (50-75 U/ml, 1 ml)

710-113-PC 1
EUR 196.8

Isotype Control, Mouse IgG1 Kappa (IGG1/1331), Purified, with BSA, 0.2 mg/mL

BNUB1331-250 1uL
EUR 57
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Isotype Control, Mouse IgG2b Kappa (IgG2b/1333), Purified, with BSA, 0.2 mg/mL

BNUB1333-250 1uL
EUR 57
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Isotype Control, Mouse IgG1 Kappa (IGG1/1331), Purified, BSA-free, 1 mg/mL

BNUM1331-50 1uL
EUR 63
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Isotype Control, Mouse IgG2a Kappa (MG2a-53), Purified, with BSA, 0.2 mg/mL

BNUB1331B-250 1uL
EUR 57
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Isotype Control, Mouse IgG2b Kappa (IgG2b/1333), Purified, BSA-free, 1 mg/mL

BNUM1333-50 1uL
EUR 63
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Isotype Control, Mouse IgG2a Kappa (MG2a-53), Purified, BSA-free, 1 mg/mL

BNUM1331B-50 1uL
EUR 63
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Rabbit Anti-Bovine Serum Albumin (BSA) IgG negative control (0 U/ml, 1 ml)

710-113-NC 1 ml
EUR 123.6

HNE antibody

20R-HG007 100 ug
EUR 280
Description: Goat polyclonal HNE antibody

Monoclonal Anti-4 HNE (4-HNE; 4-hydroxynonenal) IgG

HNE13-M 100 ul
EUR 578.4

HNE Adduct ELISA

KT-957 96 tests
EUR 864

AS Control

A26 -
EUR 330
Description: SW module for AS control

GC Control

A23 -
EUR 600
Description: SW module for GC control

LC Control

A24 -
EUR 600
Description: SW module for HPLC/CE control (pump, det, etc.)

Rat Control

DEV99RC 2 x 1 ml
EUR 60

MDP control

tlrl-mdpcl 5 mg
EUR 148.05

Rat neurofascin (Nfasc)-control Control/blocking peptide

AB-23249-CP 100ug
EUR 196.8

pMD18- Control

PVT10563 2 ug
EUR 319.2

pMD19- Control

PVT10564 2 ug
EUR 319.2

Rat IgG-PE conjugate (isotype control) (Isotype control)

20005-PE 25 tests
EUR 242.4

Control Slides

24012-1 1box
EUR 78

Canine Control

DEV99CC 2 x 1 ml
EUR 60

Dengue Control

ant-543 100µg
EUR 165
Description: Mouse Anti-Dengue Control for Lateral Flow Test

Rat IgG-HRP conjugate (isotype control) (Isotype control)

20005-HP 100 ug
EUR 196.8

Rat IgG-FITC conjugate (isotype control) (Isotype control)

20005-F 100 ug
EUR 196.8

Quality Control

abx098966-1vial 1 vial
EUR 360

Rat IgG-Biotin conjugate (isotype control) (Isotype control)

20005-B 100 ug
EUR 196.8

PIPET CONTROLLER CONTROL BOARD

357484 1/pk
EUR 104.4
Description: Falcon Liquid Handling Equipment; Falcon Pipet Controllers and Accessories

Goat IgG (-ve control for flow cytometry) (isotype control)

20011-100 100 test
EUR 123.6

ODN 2088 control

tlrl-2088c-1 1 mg
EUR 546

ODN 2395 control

tlrl-2395c-1 1 mg
EUR 546

Control siRNA Vector (pGB-control)

9500C-20 each
EUR 405.6

OOSA10387-100T - IgM NEGATIVE CONTROL Negative/Isotype Control

OOSA10387-100T 100Tests
EUR 309

OOSA10342-100UG - IgG1 NEGATIVE CONTROL Negative/Isotype Control

OOSA10342-100UG 0.1mg
EUR 219

OOSA10349-100T - IgG2a NEGATIVE CONTROL Negative/Isotype Control

OOSA10349-100T 100Tests
EUR 299

OOSA10380-100T - IgG2b NEGATIVE CONTROL Negative/Isotype Control

OOSA10380-100T 100Tests
EUR 309

OOSA10389-100T - IgG1 NEGATIVE CONTROL Negative/Isotype Control

OOSA10389-100T 100Tests
EUR 309

OOSA10397-100T - IgG2a NEGATIVE CONTROL Negative/Isotype Control

OOSA10397-100T 100Tests
EUR 309

Control FD BNP

K023M-6 6 x 1 mL
EUR 292
Description: Bi-Level

Control FD TDM

K068M-6 6 x 5 mL
EUR 205
Description: Tri-Level

EDG-1 Control

BC-009 100 uL
EUR 350

EDG-2 Control

BC-011 100 uL
EUR 350

EDG-4 Control

BC-012 100 uL
EUR 350

EDG-6 Control

BC-014 100 uL
EUR 350

EDG-7 Control

BC-016 100 uL
EUR 350

Rat Control IgG

AC034 100 ul
EUR 159.6

β-Gal Control

LV007 4 x 500 ul
EUR 195

NF-κB Control

T37559-10mg 10mg Ask for price
Description: NF-κB Control

NF-κB Control

T37559-1g 1g Ask for price
Description: NF-κB Control

NF-κB Control

T37559-1mg 1mg Ask for price
Description: NF-κB Control

NF-κB Control

T37559-50mg 50mg Ask for price
Description: NF-κB Control

NF-κB Control

T37559-5mg 5mg Ask for price
Description: NF-κB Control

Goat IgG control

31R-AG001 1 mg
EUR 104
Description: Goat Immunoglobulins Goat IgG control

Goat IgG Control

GT15900 1 mg
EUR 199.2

2'3'-cGAMP Control

tlrl-nagpap 1 mg
EUR 235.2

G3-YSD Control

tlrl-ydnac 200 µg
EUR 148.05

Rat IgG1 Control

mabg1-ctlrt 100 µg Ask for price

Mouse IgG Control

10R-I169A 250 ug
EUR 104
Description: Mouse Immunoglobulins Mouse IgG Control

human IgM control

E4A11C04 50ug
EUR 255
Description: Available in various conjugation types.

human IgE control

E4A11C05 50ug
EUR 255
Description: Available in various conjugation types.

Mouse Control IgG

AC011 100 ul
EUR 143
Description: None

Mouse IgM Control

ICIGMF-100 100 µg
EUR 239.4

Mouse IgM Control

ICIGMPU-100 100 µg
EUR 239.4

ISD Control Naked

tlrl-isdcn 200 µg
EUR 148.05

Rat IgG2a Control

mabg2a-ctlrt 100 µg
EUR 101.85

Rat IgG2a Control

mabg2a-ctlrt-05 5 x 100 µg
EUR 163.8

Rat IgG2b Control

mabg2b-ctlrt 100 µg Ask for price

human IgM control

E4A11D04 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

human IgE control

E4A11D05 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

OOSA10361-1ML - Rat IgG2a NEGATIVE CONTROL Negative/Isotype Control

OOSA10361-1ML 1ml
EUR 169

Rabbit IgG Control

31R-AR001 500 ug
EUR 94
Description: Purified Normal Rabbit IgG

human IgG1 control

E4A11C03 50ug
EUR 255
Description: Available in various conjugation types.

Rabbit Control IgG

AC005 100 ul
EUR 143
Description: A synthetic peptide corresponding to Actin (plant specific).

Human IgG1 Control

HY-P9900 5mg
EUR 776.4

Mouse IgG1 Control

ICIGG1AC750-50 50 µg
EUR 855.6

Mouse IgG1 Control

ICIGG1PU-100 100 µg
EUR 239.4

Mouse IgG3 Control

ICIGG3CFB-100 100 µg
EUR 465.6

CD3 Control Slides

ICS2005-25 25 Slides
EUR 137.81

CD5 Control Slides

ICS2006-25 25 Slides
EUR 137.81

CD8 Control Slides

ICS2007-25 25 Slides
EUR 137.81

CEA Control Slides

ICS2012-25 25 Slides
EUR 137.81

EMA Control Slides

ICS2018-25 25 Slides
EUR 137.81

LCA Control Slides

ICS2029-25 25 Slides
EUR 137.81

NSE Control Slides

ICS2031-25 25 Slides
EUR 137.81

PSA Control Slides

ICS2033-25 25 Slides
EUR 137.81

PAS Control Slides

HCS1016-25 25 Slides
EUR 137.81

Rabbit IgG Control

GWB-DLRABG 0.5 mg Ask for price

ODN TTAGGG control

tlrl-ttagc-1 1 mg
EUR 546

Human IgA2 Control

maba2-ctrl 100 µg
EUR 101.85

Human IgA2 Control

maba2-ctrl-05 5 x 100 µg
EUR 163.8

Mouse Control IgG1

mabg1-ctrlm 100 µg
EUR 99.75

Mouse Control IgG1

mabg1-ctrlm-05 5 x 100 µg
EUR 163.8

Human IgG1 Control

TP1357-10mg 10mg Ask for price
Description: Human IgG1 Control

Human IgG1 Control

TP1357-1g 1g Ask for price
Description: Human IgG1 Control

Human IgG1 Control

TP1357-1mg 1mg Ask for price
Description: Human IgG1 Control

Human IgG1 Control

TP1357-50mg 50mg Ask for price
Description: Human IgG1 Control

Human IgG1 Control

TP1357-5mg 5mg Ask for price
Description: Human IgG1 Control

human IgG1 control

E4A11D03 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

RNA Extraction Control 670

BIO-38040 100 Reactions Ask for price

RNA Extraction Control 670

BIO-38041 500 Reactions Ask for price

RNA Extraction Control 560

BIO-38044 100 Reactions Ask for price

RNA Extraction Control 560

BIO-38045 500 Reactions Ask for price

RNA Extraction Control 610

BIO-38048 100 Reactions Ask for price

RNA Extraction Control 610

BIO-38049 500 Reactions Ask for price

OOSA10379-250UG - Rat IgG2c NEGATIVE CONTROL Negative/Isotype Control

OOSA10379-250UG 0.25mg
EUR 319

Mouse (mrl/lpr) serum containing autoantibodies to HNE

HNE31-M 100 ul
EUR 578.4

Insulin rat control

DEV8811C 96
EUR 64

Mouse IgG2a Control

ICIGG2AB-100 100 µg
EUR 239.4

Mouse IgG2a Control

ICIGG2ACFB-100 100 µg
EUR 387.6

Mouse IgG2b Control

ICIGG2BCFB-100 100 µg
EUR 387.6

CD43 Control Slides

ICS2010-25 25 Slides
EUR 137.81

PSAP Control Slides

ICS2034-25 25 Slides
EUR 137.81

Gram Control Slides

HCS1011-25 25 Slides
EUR 137.81

Iron Control Slides

HCS1013-25 25 Slides
EUR 137.81

PTAH Control Slides

HCS1018-25 25 Slides
EUR 137.81

CHO Control Antigen

F063 50 ul
EUR 262.8
Description: CHO Control Antigen by Cygnus Technologies is available in Europe via Gentaur.

SF9 Control Antigen

F127 50 ul
EUR 288
Description: SF9 Control Antigen by Cygnus Technologies is available in Europe via Gentaur.

PER.C6 Control Antigen

F536 70 ul
EUR 400.8
Description: PER.C6 Control Antigen by Cygnus Technologies is available in Europe via Gentaur.

Mouse Control IgG2a

mabg2a-ctrlm 100 µg
EUR 105

Mouse Control IgG2a

mabg2a-ctrlm-05 5 x 100 µg
EUR 163.8

Mouse IgG2b Control

mabg2b-ctrlm 100 µg Ask for price

Mouse IgG2b Control

mabg2b-ctrlm-05 5 x 100 µg
EUR 163.8

EUROSTAR 200 control Overhead Stirrer with wireless control unit - EACH

STI2876 EACH
EUR 6112.8

EUROSTAR 100 control Overhead Stirrer with wireless control unit - EACH

STI2878 EACH
EUR 4104

FMK Negative Control

1122-100 each
EUR 210

FMK Negative Control

1122-20C each
EUR 210

RGD Negative Control

4099641.2001 0.5 mg
EUR 62.9

RGD Negative Control

4099641.2002 1 mg
EUR 106.79

RGD Negative Control

4099641.2003 5 mg
EUR 258.41

IgG control Antibody

abx234182-100ug 100 ug
EUR 577.2

IgG control antibody

E39-09882 100ug/100ul
EUR 225
Description: Available in various conjugation types.

IgG control antibody

CAF50392-100ug 100ug
EUR 338

Kappa Control Slides

ICS2027-25 25 Slides
EUR 137.81

Fites Control Slides

HCS1009-25 25 Slides
EUR 137.81

Mucin Control Slides

HCS1015-25 25 Slides
EUR 137.81

IgG control antibody

PAab09882 100 ug
EUR 463.2

pGL3- Control Plasmid

PVT1306 2 ug
EUR 319.2

MDCKII Control Cells

S0014005 One Frozen vial
EUR 420

Mucate Control Broth

M1227-500G 1 unit
EUR 35.17
Description: Mucate Control Broth

Mucin (Control Slides)

TCS0016-100 100 Slides
EUR 847.2

Mucin (Control Slides)

TCS0016-25 25 Slides
EUR 278.4

Mucin (Control Slides)

TCS0016-5 5 Slides
EUR 117.6

IgG control Antibody

abx234182-100g 100 µg
EUR 350

Mouse Lipin-1 Control/blocking peptide control/blocking peptide #1

LPN11-P 100 ug
EUR 196.8

Mouse Lipin-2 Control/blocking peptide control/blocking peptide #1

LPN21-P 100 ug
EUR 196.8

Mouse Lipin-3 Control/blocking peptide control/blocking peptide #1

LPN31-P 100 ug
EUR 196.8

EUROSTAR 60 control Overhead Stirrer with wireless control unit - EACH

STI2886 EACH
EUR 3256.2

OOSA10362-100UG - IgG2a NEGATIVE CONTROL: Biotin Negative/Isotype Control

OOSA10362-100UG 0.1mg
EUR 169

TRAF6 Control Peptide

4095549.0001 1 mg
EUR 368.55

Desmin Control Slides

ICS2017-25 25 Slides
EUR 137.81

Lambda Control Slides

ICS2028-25 25 Slides
EUR 137.81

TRAF6 Control Peptide

H-7606.0001 1.0mg
EUR 607.2
Description: Sum Formula: C139H232N34O42; CAS# [852690-80-3] net

Amoeba Control Slides

HCS1003-25 25 Slides
EUR 137.81

Fungus (Control Slides)

TCS0005-100 100 Slides
EUR 847.2

Fungus (Control Slides)

TCS0005-25 25 Slides
EUR 278.4

Fungus (Control Slides)

TCS0005-5 5 Slides
EUR 117.6

Control LQ RF/CRP

K073M-6 6 x 2 mL
EUR 409
Description: Tri-Level

EZ‐M. Hyo Control

TC-9116-096 each
EUR 90

Recombinant purified HA-tag -Protein (~9 kda) control WB +ve control

HA11-C 100 ul
EUR 343.2

unpurified control to 011-3a

011-3b.2 100µl
EUR 143

ViaCheck Viability Control 100%

VC50B-20 20 ml
EUR 581.5
Description: ViaCheck Viability Control 100% mimic the characteristics of live and dead cells in the trypan blue dye exclusion method and may be used to support validation and QC of image-based cell viability analyzers 

Deer IgG, semi-pure for ELISA (Control, non-immune, isotype control)

20024-2 100 ug
EUR 270

Recombinant purified Myc-tag -Protein (~9 kda) control WB +ve control

MYC11-C 100 ul
EUR 343.2

 

Immune evasion in renal cell carcinoma: biology, scientific translation, future instructions

 

Focused therapies and immune checkpoint inhibitors have superior the therapy panorama of Renal Cell Carcinoma (RCC) during the last decade. Whereas checkpoint inhibitors have demonstrated survival profit and are at present accredited within the front-line and second-line settings, major and secondary resistance is widespread.

A complete understanding of the mechanisms of immune evasion in RCC is due to this fact crucial to the event of efficient mixture therapy methods. This text opinions the present understanding of the completely different, but coordinated, mechanisms adopted by RCC cells to evade immune killing; summarizes varied facets of scientific translation thus far, together with the at present registered RCC scientific trials exploring brokers together with checkpoint inhibitors; and offers views on the present panorama and future instructions for the sphere.

 

Eukaryotic cell biology is temporally coordinated to help the energetic calls for of protein homeostasis

Yeast physiology is temporally regulated, this turns into obvious below nutrient-limited situations and ends in respiratory oscillations (YROs). YROs share options with circadian rhythms and work together with, however are impartial of, the cell division cycle. Right here, we present that YROs minimise power expenditure by limiting protein synthesis till enough sources are saved, whereas sustaining osmotic homeostasis and protein high quality management.

Though nutrient provide is fixed, cells sequester and retailer metabolic sources through elevated transport, autophagy and biomolecular condensation. Replete shops set off elevated H+ export which stimulates TORC1 and liberates proteasomes, ribosomes, chaperones and metabolic enzymes from non-membrane certain compartments. This facilitates translational bursting, liquidation of storage carbohydrates, elevated ATP turnover, and the export of osmolytes.

We suggest that dynamic regulation of ion transport and metabolic plasticity are required to keep up osmotic and protein homeostasis throughout remodelling of eukaryotic proteomes, and that bioenergetic constraints chosen for temporal organisation that promotes oscillatory behaviour.

Dysregulation of membership cell biology in idiopathic pulmonary fibrosis

 

Idiopathic pulmonary fibrosis (IPF) is a progressive, persistent fibrotic lung illness with an irreversible decline of lung perform. “Bronchiolization”, characterised by ectopic look of airway epithelial cells within the alveolar areas, is without doubt one of the attribute options within the IPF lung.

Primarily based on the data that membership cells are the foremost epithelial secretory cells in human small airways, and their main secretory product uteroglobin (SCGB1A1) is considerably elevated in each serum and epithelial lining fluid of IPF lung, we hypothesize that human airway membership cells contribute to the pathogenesis of IPF.

By assessing the transcriptomes of the only cells from human lung of management donors and IPF sufferers, we recognized two SCGB1A1+ membership cell subpopulations, extremely expressing MUC5B, a major genetic threat issue strongly related with IPF, and SCGB3A2, a marker heterogeneously expressed within the membership cells, respectively. Apparently, the mobile proportion of SCGB1A1+MUC5B+ membership cells was considerably elevated in IPF sufferers, and this membership cell subpopulation extremely expressed genes associated to mucous manufacturing and immune cell chemotaxis.

In distinction, although the mobile proportion didn’t change, the molecular phenotype of the SCGB1A1+SCGB3A2high membership cell subpopulation was considerably altered in IPF lung, with elevated expression of mucins, cytokine and extracellular matrix genes. The one cell transcriptomic evaluation reveals the mobile and molecular heterogeneity of membership cells, and supply novel insights into the organic features of membership cells within the pathogenesis of IPF.

 

Metabolic and Redox regulation of cardiovascular stem cell biology and pathology

Significance: Cardiovascular stem cells are essential for regeneration and restore of broken tissue. Current Advances: Pluripotent stem cells have a novel metabolism, which is adopted to their energetic and biosynthetic demand as quickly proliferating cells. Stem cell differentiation requires an distinctive metabolic flexibility permitting for metabolic reworking between glycolysis and oxidative phosphorylation.
Essential points: Respiration is related to the technology of reactive oxygen species (ROS) by the mitochondrial respiratory chain. But in addition the membrane-bound protein nicotinamide adenine dinucleotide phosphate oxidase (NADPH oxidase, NOX) contributes to ROS ranges. ROS performs a major position in stem cell differentiation and tissue renewal but in addition trigger senescence and contribute to tissue growing older.
Future instructions: For utilization of stem cells in therapeutic approaches, a deep understanding of the molecular mechanisms how metabolism and the mobile redox state regulates stem cell differentiation is required. Modulating the redox state of stem cells utilizing antioxidative brokers could also be appropriate to boost exercise of endothelial progenitor cells.

Thiol switches in membrane proteins – Additionalcellular redox regulation in cell biology

Redox-mediated sign transduction is determined by the enzymatic manufacturing of second messengers similar to hydrogen peroxide, nitric oxide and hydrogen sulfite, in addition to particular, reversible redox modifications of cysteine-residues in proteins.
So-called thiol switches induce as an illustration conformational modifications in particular proteins that regulate mobile pathways e.g., cell metabolism, proliferation, migration, gene expression and irritation.
Discount, oxidation and disulfide isomerization are managed by oxidoreductases of the thioredoxin household, together with thioredoxins, glutaredoxins, peroxiredoxins and protein dsisulfide isomerases. These proteins are situated in several mobile compartments, work together with substrates and catalyze particular reactions.
Apparently, a few of these proteins are launched by cells. Their extracellular features and usually extracellular redox management have been broadly underestimated. Right here, we give an perception into extracellular redox signaling, extracellular thiol switches and their regulation by secreted oxidoreductases and thiol-isomerases, a subject whose significance has been scarcely studied up to now, possible attributable to methodological limitations.
We concentrate on the secreted redox proteins and characterised thiol switches within the ectodomains of membrane proteins, similar to integrins and the metalloprotease ADAM17, that are among the many best-characterized proteins and talk about their underlying mechanisms and organic implications.

pAAV-RC1 Vector

VPK-421 10 µg
EUR 530

pAAV-RC3 Vector

VPK-423 10 µg
EUR 530

pAAV-RC4 Vector

VPK-424 10 µg
EUR 530

pAAV-RC5 Vector

VPK-425 10 µg
EUR 530

pAAV-RC6 Vector

VPK-426 10 µg
EUR 530

pAAV-DJ vector

PVT12151 2 ug
EUR 525.6

pAAV-DJ Vector

VPK-420-DJ 10 µg
EUR 530

pAAV-DJ/8 Vector

VPK-420-DJ-8 10 µg
EUR 530

pAAV-GFP Control Vector

AAV-400 10 µg
EUR 455

pAAV-Cre Control Vector

AAV-401 10 µg
EUR 679.2
Description: Use this control vector to co-transfect along with AAV packaging vectors to produce a recombinant AAV control.

pAAV-LacZ Control Vector

AAV-402 10 µg
EUR 679.2
Description: Use this control vector to co-transfect along with AAV packaging vectors to produce a recombinant AAV control.

pAAV-MCS Expression Vector

VPK-410 10 µg
EUR 530

pAAV-IRES-Neo Expression Vector

VPK-416 10 µg
EUR 776.4
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-IRES-GFP Expression Vector

VPK-418 10 µg
EUR 530

pAAV-IRES-Bsd Expression Vector

VPK-419 10 µg
EUR 776.4
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-IRES-Puro Expression Vector

VPK-415 10 µg
EUR 776.4
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-IRES-Hygro Expression Vector

VPK-417 10 µg
EUR 776.4
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-MCS Promoterless Expression Vector

VPK-411 10 µg
EUR 530

Green Kit. Baculovirus GFP vector.

K20 1 Kit
EUR 695
Description: Protein expression

ProGreen. Baculovirus GFP marker vector.

A1 25 ul
EUR 420
Description: Protein expression

pVL1393. General baculovirus plasmid vector.

B1 50 ul
EUR 340
Description: Protein expression

pAAV-RC6

PVT14647 2 ug
EUR 843.6

ProEasy. Vector for easy construction of recombinant baculoviruses.

A10S 25 ul
EUR 695
Description: Protein expression

pAcAB3. Baculovirus plasmid vector for expression of up to 3 proteins.

B2 50 ul
EUR 420
Description: Protein expression

pAB-bee. Baculovirus plasmid vector for secreted and transmembrane proteins.

B3 50 ul
EUR 495
Description: Protein expression

ProFold-PDI. Baculovirus chaperone vector for expression of cysteine-rich proteins.

A7 25 ul
EUR 830
Description: Protein expression

ProFold-C1. Baculovirus chaperone vector for expression of cytoplasmic and nuclear proteins.

A2 25 ul
EUR 830
Description: Protein expression

ProFold-C2. Baculovirus chaperone vector for expression of cytoplasmic and nuclear proteins.

A3 25 ul
EUR 830
Description: Protein expression

ProFold-ER1. Baculovirus chaperone vector for expression of secreted and membrane proteins.

A4 25 ul
EUR 830
Description: Protein expression

pAAV- RC

PVT2103 2 ug
EUR 289.2

C1 Kit. Baculovirus chaperone vectors for cytoplasmic and nuclear proteins.

K21 1 Kit
EUR 995
Description: Protein expression

C2 Kit. Baculovirus chaperone vectors for cytoplasmic and nuclear proteins.

K22 1 Kit
EUR 995
Description: Protein expression

ER1 Kit. Baculovirus chaperone vectors for expression of secreted and membrane proteins.

K23 1 Kit
EUR 995
Description: Protein expression

ER1-bee Kit. Baculovirus chaperone vectors for expression of secreted and membrane proteins.

K24 1 Kit
EUR 995
Description: Protein expression

pAAV- MCS Plasmid

PVT2102 2 ug
EUR 289.2

pAAV-CAG-GFP

PVT17666 2 ug
EUR 409.2

pAAV-fNPY-GFP

PVT14636 2 ug
EUR 718.8

pAAV- IRES- ZsGreen1

PVT11044 2 ug
EUR 361.2

pAAV- ZsGreen1- shRNA

PVT11045 2 ug
EUR 444

pAAV-RSV-SpCas9

PVT17629 2 ug
EUR 360

pAAV- IRES- hrGFP Plasmid

PVT2104 2 ug
EUR 319.2

pAAV-EF1a-DIO-mCherry

PVT17841 2 ug
EUR 360

pAAV- CMV- mCherry- U6- sgRNA

PVT11046 2 ug
EUR 361.2

pAAV-hSyn-eNpHR 3.0-EYFP

PVT19063 2 ug
EUR 309.6

pAAV-hSyn-hChR2(H134R)-mCherry

PVT19026 2 ug
EUR 309.6

pAAV-EF1a-DIO-hM3D(Gq)-mCherry

PVT17847 2 ug
EUR 360

pAAV-MCS-Ppargc1a-m-FLAG-HA

PVT18341 2 ug
EUR 360

pAB-bee-FH. FLAG and His tagging of secreted and transmembrane proteins in baculovirus system.

B3FH 50 ul
EUR 495
Description: Protein expression

pAB-bee-8xHis. His tagging of secreted and transmembrane proteins in baculovirus system.

B3H 50 ul
EUR 495
Description: Protein expression

pAB-6xHis. His tagging of cytoplasmic and nuclear proteins in baculovirus system.

B4 50 ul
EUR 295
Description: Protein expression

pAB-GST. GST tagging of cytoplasmic and nuclear proteins in baculovirus system.

B5 50 ul
EUR 295
Description: Protein expression

pAB-MBP. MBP tagging of cytoplasmic and nuclear proteins in baculovirus system.

B6 50 ul
EUR 395
Description: Protein expression

pAB-6xHis-MBP. His and MBP tagging of cytoplasmic and nuclear proteins in baculovirus system.

B7 50 ul
EUR 495
Description: Protein expression

pVL-GFP. GFP tagging of cytoplasmic and nuclear proteins in baculovirus system.

B8 50 ul
EUR 395
Description: Protein expression

pVL-FH. Flag and His tagging of cytoplasmic and nuclear proteins in baculovirus system.

B9 50 ul
EUR 295
Description: Protein expression

BV-p53. Recombinant baculovirus expressing p53 (wt).

BV53 1 ml
EUR 980
Description: Drug discovery, Transcription factors, baculovirus

NC (negative control baculovirus)

C13 1 ml
EUR 195
Description: Protein expression

GC (green control baculovirus expressing GFP)

C14 1 ml
EUR 195
Description: Protein expression

GCP (green control plasmid for GFP expression)

C15 50 ul
EUR 145
Description: Protein expression

BV-ADRA1D. Recombinant baculovirus expressing Adrenergic Receptor alpha 1D.

GA11 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-ADRA2A. Recombinant baculovirus expressing Adrenergic Receptor alpha 2A.

GA15 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-ADRA2C. Recombinant baculovirus expressing Adrenergic Receptor alpha 2C.

GA19 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-ADRB2. Recombinant baculovirus expressing Adrenergic Receptor beta 2

GA23 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-ADRA1A. Recombinant baculovirus expressing Adrenergic Receptor alpha 1A (ADRA1A)

GA3 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-ADRA1B. Recombinant baculovirus expressing Adrenergic Receptor alpha 1B.

GA7 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-AGTR1. Recombinant baculovirus expressing angiotensin II receptor (AGTR1).

GAT1 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-DRD1. Recombinant baculovirus expressing Dopamine receptor 1 (DRD1).

GD3 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-DRD2. Recombinant baculovirus expressing Dopamine receptor 1 (DRD2).

GD5 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HRH1. Recombinant baculovirus expressing Histamine receptor (HRH1).

GH41 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HRH2. Recombinant baculovirus expressing Histamine receptor (HRH2).

GH45 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HRH3. Recombinant baculovirus expressing Histamine receptor (HRH3).

GH49 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HRH4. Recombinant baculovirus expressing Histamine receptor (HRH4).

GH53 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-CHRM1. Recombinant baculovirus expressing Muscarinic acetylcholine receptor 1 (CHRM1).

GM1 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-CHRM2. Recombinant baculovirus expressing Muscarinic acetylcholine receptor 2 (CHRM2).

GM5 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HTR1A. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 1A.

GS27 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HTR1B. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 1B.

GS31 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HTR1D. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 1D.

GS35 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HTR1F. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 1F.

GS37 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HTR2A. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 2A.

GS39 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HTR2B. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 2B.

GS43 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HTR2C. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 2C.

GS47 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HTR5A. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 5A.

GS51 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

BV-HTR7B. Recombinant baculovirus expressing 5-hydroxytryptamine (serotonin) receptor 7B.

GS55 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

FoldHelper-57P. Recombinant baculovirus expressing ERp57 and PDI.

H17 1 ml
EUR 295
Description: Protein expression

FoldHelper-37. Recombinant baculovirus expressing cdc37.

H18 1 ml
EUR 395
Description: Protein expression

FoldHelper-ER3. Recombinant baculovirus expressing human ER chaperones.

H6 2 ml
EUR 695
Description: Protein expression

Controls Kit. Baculovirus controls.

K26 1 Kit
EUR 295
Description: Protein expression

THRB-LBD. Purified GST-tagged human Thyroid hormone receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N1A2 50 ug
EUR 660
Description: Drug discovery, Nuclear receptors, purified recombinant protein

RARA-LBD. Purified GST-tagged human Retinoic acid receptor alpha ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N1B1 50 ug
EUR 498
Description: Drug discovery, Nuclear receptors, purified recombinant protein

RARB-LBD. Purified GST-tagged human Retinoic acid receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N1B2 50 ug
EUR 420
Description: Drug discovery, Nuclear receptors, purified recombinant protein

RARG-LBD. Purified GST-tagged human Retinoic acid receptor gamma ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N1B3 50 ug
EUR 498
Description: Drug discovery, Nuclear receptors, purified recombinant protein

PPARG-LBD. Purified GST-tagged human Peroxisome proliferator-activated receptor gamma ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N1C3 50 ug
EUR 720
Description: Drug discovery, Nuclear receptors, purified recombinant protein

LXRB-LBD. Purified GST-tagged human Liver X receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N1H2 50 ug
EUR 498
Description: Drug discovery, Nuclear receptors, purified recombinant protein

LXRA-LBD. Purified GST-tagged human Liver X receptor alpha ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N1H3 50 ug
EUR 360
Description: Drug discovery, Nuclear receptors, purified recombinant protein

FXR-LBD. Purified GST-tagged human Farnesoid X receptor ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N1H4 50 ug
EUR 360
Description: Drug discovery, Nuclear receptors, purified recombinant protein

RXRA-LBD. Purified GST-tagged human Retinoid X receptor alpha ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N2B1 50 ug
EUR 360
Description: Drug discovery, Nuclear receptors, purified recombinant protein

RXRB-LBD. Purified GST-tagged human Retinoid X receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N2B2 50 ug
EUR 360
Description: Drug discovery, Nuclear receptors, purified recombinant protein

RXRG-LBD. Purified GST-tagged human Retinoid X receptor gamma ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N2B3 50 ug
EUR 360
Description: Drug discovery, Nuclear receptors, purified recombinant protein

ERb-LBD. Purified GST-tagged human Estrogen receptor beta LBD. Applications: Ligand-binding and coregulator displacement assays.

N3A2 50 ug
EUR 495
Description: Drug discovery, Nuclear receptors, purified recombinant protein

ESRRA-LBD. Purified GST-tagged human Estrogen-related receptor alpha ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N3B1 50 ug
EUR 980
Description: Drug discovery, Nuclear receptors, purified recombinant protein

ESRRB-LBD. Purified GST-tagged human Estrogen-related receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N3B2 50 ug
EUR 498
Description: Drug discovery, Nuclear receptors, purified recombinant protein

ESRRG-LBD. Purified GST-tagged human Estrogen-related receptor gamma ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.

N3B3 50 ug
EUR 360
Description: Drug discovery, Nuclear receptors, purified recombinant protein

BV-Tau412. Recombinant baculovirus expressing 412 aa Tau isoform.

PD13 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

BV-Tau412TR. Recombinant baculovirus expressing 412 aa Tau isoform. T39-R mutant.

PD14 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

BV-Tau412KE. Recombinant baculovirus expressing 412 aa Tau isoform. K267-E mutant.

PD15 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

BV-Synuclein. Recombinant baculovirus expressing alpha synuclein.

PD17 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

BV-Syn-GFP. Recombinant baculovirus expressing alpha synuclein-GFP fusion.

PD21 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

BV-SOD1. Recombinant baculovirus expressing SOD1.

PD25 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

BV-SOD1-GFP. Recombinant baculovirus expressing SOD1-GFP fusion.

PD29 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

BV-Tau352. Recombinant baculovirus expressing 352 aa Tau isoform.

PD3 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

BV-Tau383. Recombinant baculovirus expressing 383 aa Tau isoform.

PD7 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

BV-Tau381. Recombinant baculovirus expressing 381 aa Tau isoform.

PD9 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

BV-PR-LBD. Recombinant baculovirus expressing Progesterone receptor LBD.

S15 1 ml
EUR 1250
Description: Drug discovery, Nuclear receptors, baculovirus

BV-MR-LBD. Recombinant baculovirus expressing Mineralocorticoid receptor LBD.

S27 1 ml
EUR 1250
Description: Drug discovery, Nuclear receptors, baculovirus

MR-LBD. Purified GST-tagged MR LBD in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays.

S28 50 ug
EUR 1240
Description: Drug discovery, Nuclear receptors, purified recombinant protein

BV-GR-LBD. Recombinant baculovirus expressing Glucocorticoid receptor LBD.

S33 1 ml
EUR 1250
Description: Drug discovery, Nuclear receptors, baculovirus

BV-GR. Recombinant baculovirus expressing Glucocorticoid receptor.

S35 1 ml
EUR 1250
Description: Drug discovery, Nuclear receptors, baculovirus

BV-PXR-LBD. Recombinant baculovirus expressing Pregnane X receptor LBD.

S36 1 ml
EUR 1250
Description: Drug discovery, Nuclear receptors, baculovirus

BV-AhR. Recombinant baculovirus expressing Aryl hydrocarbon receptor LBD.

S41 1 ml
EUR 1250
Description: Drug discovery, Nuclear receptors, baculovirus

AhR-LBD. Purified GST-tagged human Arylhydrocarbon receptor LBD in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays.

SAh90 50 ug
EUR 980
Description: Drug discovery, Nuclear receptors, purified recombinant protein

CAR. Purified GST-tagged human Constitutive andristane receptor in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays.

SC90 50 ug
EUR 1100
Description: Drug discovery, Nuclear receptors, purified recombinant protein

ERa-LBD (Hsp90). Purified GST-tagged human Estrogen receptor alpha LBD in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays.

SEa90 50 ug
EUR 1100
Description: Drug discovery, Nuclear receptors, purified recombinant protein

ERb-LBD (Hsp90). Purified GST-tagged human Estrogen receptor beta LBD in complex with Hsp90. Applications: ligand-binding and coregulator displacement studies.

SEb90 50 ug
EUR 760
Description: Drug discovery, Nuclear receptors, purified recombinant protein

GR-LBD. GR-LBD. Purified GST-tagged human Estrogen receptor alpha LBD in complex with Hsp90. For ligand-binding and coregulator displacement studies.

SG90 50 ug
EUR 1240
Description: Drug discovery, Nuclear receptors, purified recombinant protein

PR-LBD. Purified GST-tagged human Progesterone receptor LBD in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays.

SP90 50 ug
EUR 498
Description: Drug discovery, Nuclear receptors, purified recombinant protein

PXR-LBD. Purified GST-tagged human Pregnane X receptor in complex with Hsp90. Applications: Ligand-binding and coregulator displacement assays.

SPX90 50 ug
EUR 498
Description: Drug discovery, Nuclear receptors, purified recombinant protein

ProFectin. Transfection reagent for insect cells.

T10 50 ul
EUR 160
Description: Transfection

ProFectin. Transfection reagent for insect cells.

T20 100 ul
EUR 295
Description: Transfection

pAAVS1-SA-T2A-Neo-MCS Donor Vector

AC2002 10 μg
EUR 665

pAAVK-EF1α -MCS AAVanced Cloning and Expression Vector

AAV502A-1 10 ug
EUR 614

pAAVS1-SA-T2A-Neo-CAG-MCS-SV40pA Donor Vector

AC2302 10 μg
EUR 665

pAAVS1-SA-T2A-Puro-CAG-MCS-SV40pA Donor Vector

AC2301 10 μg
EUR 665

pAAVS1-SA-T2A-HygR-CAG-MCS-SV40pA Donor Vector

AC2303 10 μg
EUR 665

pAAVS1-SA-T2A-Neo-SV40pA-MCS-SFFV Donor Vector

AC2402 10 μg
EUR 665

pAAVS1-SA-T2A-Neo-CAG-dCas9-VPR-pA Donor Vector

AC8302 10 μg
EUR 805

pAAVS1-SA-T2A-Neo-CAG-dCas9-KRAB-pA Donor Vector

AC7302 10 μg
EUR 805

pAAVS1-SA-T2A-Neo-CAG-EGFP-SV40pA Control Donor Vector

AC9312 10 μg
EUR 665

pAAVS1-SA-T2A-Puro-CAG-EGFP-SV40pA Control Donor Vector

AC9311 10 μg
EUR 665

pAAVK-EF1α -MCS-T2A-EGFP AAVanced Cloning and Expression Vector

AAV526A-1 10 ug
EUR 614

pAAVK-EF1α -MCS-T2A-Puro AAVanced Cloning and Expression Vector

AAV527A-1 10 ug
EUR 614

pAAVK-EF1α –MCS-T2A-mRFP AAVanced Cloning and Expression Vector

AAV528A-1 10 ug
EUR 614

pAAVS1-SA-T2A-Puro-SV40pA-EGFP-SFFV Control Donor Vector

AC9411 10 μg
EUR 665

pAAVS1-SA-T2A-Puro-CAG-copGFP-SV40pA Control Donor Vector

AC9321 10 μg
EUR 665

pAAVS1-SA-T2A-Puro-SV40pA-copGFP-SFFV Control Donor Vector

AC9421 10 μg
EUR 665

pAAVK-EF1α-MCS1-CMV-MCS2 AAVanced Cloning and Expression Vector

AAV503A-1 10 ug
EUR 614

pAAVK-EF1α-MCS1-CMV-EGFP AAVanced Cloning and Expression Vector

AAV536A-1 10 ug
EUR 614

pAAVK-EF1α-MCS1-CMV-Puro AAVanced Cloning and Expression Vector

AAV537A-1 10 ug
EUR 614

pAAVK-EF1α-MCS1-CMV-mRFP AAVanced Cloning and Expression Vector

AAV538A-1 10 ug
EUR 614

AAVS1 Safe Harbor cDNA/miRNA Donor Vector [pAAVS1D-PGK.MCS-EF1a.copGFPpuro]

GE602A-1 10 ug
EUR 1190

pAAVS1-SA-T2A-Neo-CAG-rtTA-pA-TRE-dCas9-VPR-pA Donor Vector

AI8902 10 μg
EUR 875

pAAVS1-SA-T2A-Neo-CAG-rtTA-pA-TRE-dCas9-KRAB-pA Donor Vector

AI7902 10 μg
EUR 875

pAAVS1-SA-T2A-Puro-CAG-rtTA-SV40pA-TRE-MCS-SV40pA Donor Vector

AI3901 10 μg
EUR 875

pAAVS1-SA-T2A-Neo-CAG-rtTA-SV40pA-TRE-MCS-SV40pA Donor Vector

AI3902 10 μg
EUR 875

pAAVS1-SA-T2A-HygR-CAG-rtTA-SV40pA-TRE-MCS-SV40pA Donor Vector

AI3903 10 μg
EUR 875

AAVS1 Safe Harbor Positive Control Donor Vector [pAAVS1D-CMV.RFP-EF1a.copGFPpuro]

GE603A-1 10 ug
EUR 1190

pAAVS1-SA-T2A-Puro-CAG-EGFP-SV40pA-SV40pA-MCS-SFFV Donor Vector

AC4411 10 μg
EUR 665

Rc3h2 ORF Vector (Rat) (pORF)

ORF074641 1.0 ug DNA
EUR 607.2

RC3H2 ORF Vector (Human) (pORF)

ORF008684 1.0 ug DNA
EUR 114

RC3H1 ORF Vector (Human) (pORF)

ORF028827 1.0 ug DNA
EUR 486

Rc3h1 ORF Vector (Mouse) (pORF)

ORF055784 1.0 ug DNA
EUR 607.2

Rc3h2 ORF Vector (Mouse) (pORF)

ORF055785 1.0 ug DNA
EUR 607.2

RC3H1-IT1 ORF Vector (Human) (pORF)

ORF028828 1.0 ug DNA Ask for price

pAAV2- 8

PVT11048 2 ug
EUR 361.2

pAAV5

PVT11596 2 ug
EUR 364.8

PAAF1 ORF Vector (Human) (pORF)

ORF007465 1.0 ug DNA
EUR 114

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